Release date: 2007-03-19
Scientists have made a groundbreaking achievement by creating the world's first beating "miniature heart" in the lab. This remarkable development, led by researchers at the Israel Institute of Technology, could revolutionize the treatment of heart disease and offer new hope to millions of patients worldwide. For the first time, scientists have successfully generated functional heart tissue that includes all the essential cell types needed for a working heart.
The miniature heart is smaller than one square centimeter and features tiny blood vessels that closely resemble the complex structures found in a real heart. The team used embryonic stem cells to produce three critical types of cells—cardiomyocytes (heart muscle cells), endothelial cells (which line blood vessels), and fibroblasts (supportive connective tissue cells). These were then placed into a biodegradable scaffold, where they naturally merged over several weeks to form a small, pulsating piece of heart tissue.
This breakthrough is significant because it demonstrates the ability to grow and functionally integrate different heart cell types in a controlled environment. It opens up new possibilities for repairing damaged heart tissue and could eventually lead to the creation of transplantable heart valves, blood vessels, or even full-sized hearts.
Professor Jeremy Pearson from the British Heart Foundation commented on the potential impact of this research, stating, "We are excited about the future of stem cell technology as a 'toolbox' for repairing damaged hearts caused by heart attacks. In the long term, we may even be able to engineer heart valves, blood vessels, or even entire hearts for transplantation." This discovery marks a major step forward in regenerative medicine and brings us closer to a future where heart failure can be effectively treated with lab-grown tissues.
Source: Shanghai Medical Device Industry Association
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