Network Theory: Another Innovation in TCM Theory

Business Club February 17th

On February 13th, at the Great Hall of the People in Beijing, a “peak forum on the construction of the theory of contextual connections and its guidance on the prevention and treatment of vascular lesions” was reported. The “973 context” project under the auspices of Academician Wu Yiling and undertaken by eight domestic research institutes “Construction of contextual theory” Its basic research on the prevention and treatment of vascular lesions has yielded major research results: This study proposes that the meridians of Chinese medicine include meridians and veins, and the theory of veins and meridian theory are related to each other and are relatively independent to form a complete meridian theory; the core theories of vein theory are proposed. The management of Ying Wei was used to control the level of cardiovascular disease, arrhythmia, and chronic heart failure, and the characteristics of the pathogenesis of traditional Chinese medicine and medication rules were summed up. Extensive basic and clinical studies revealed the correlation between camping gas, endothelium, and air and adventitia. Sex, and evidence-based medical evaluation confirmed the Tongxinluo capsule treatment of acute myocardial infarction without reflux, Shensongyangxin capsule treatment of arrhythmias significant effect, for the first time the formation of vascular lesions, including acute myocardial infarction, cerebral infarction, diabetic blood vessels The complications and other major diseases have the guiding theory of systemic theory - context theory.

On the same day, the launching ceremony of the “The Theory of Threads” focused on reflecting the original research results and fully expounding the theory of Chinese medicine veins was held. The book was presided over by academician Wang Yongyan, edited by Academician Wu Yiling, and published by China Science and Technology Publishing House.

Academician Wu Yiling and the 973 research team he led systematically collated the discussion and treatment of contextual theories in ancient literature, and based on the “three-dimensional network system” developed by his theory of collaterals, he proposed that the generalized collaterals should be divided into meridians and veins. It is not only the network that runs blood as its main function in the meridian system, but also an important part of the heart (lung)-blood-pulse circulation system that maintains blood flow. It is also an independent body organ, whose function is to run blood to the whole body to play a role in nutrition Metabolism. "Context" has a high correlation with small blood vessels and micro-vessels, including microcirculation, in Western medicine, and has become a binding point for the study of vascular lesions by integrated Chinese and Western medicine.

"The Theory of Threads" puts forward the core theory of the context theory - the leveling of the Yingwei system, reveals the correlation between the qi and the endometrium, the weiqi and the adventitia, and clarifies the pathogenesis and pathogenesis of the "veno-vascular system disease". The inherent laws of syndrome differentiation and treatment. The project through a clinical investigation of 3469 patients with vascular lesions and through complex system entropy analysis methods, clarifies the complications of complications such as "deficiency and stagnation," "distemper," and "constriction," and the pathogenesis of vascular lesions. Summarizes the drug-dissolving rule of “retrieve and clear” and forms the characteristics of the representative drug Tongxinluo Capsule. Through experimental studies, it was revealed that the psychosocial and psychological factors cause aggravation of vascular lesions through systemic neuroendocrine-immune homeostasis disorders, providing an experimental basis for the early intervention of vascular lesions.

Acute cardiovascular and cerebrovascular events and diabetic microvascular complications have become major diseases that seriously endanger the lives of patients. This study proposes that the common core mechanism of these three types of diseases is “microvascular injury”, which is a bottleneck restricting the improvement of clinical efficacy. Experimental and clinical evidence-based evaluation confirmed that Tongxinluo significantly reduced the myocardial no-reflow after interventional myocardial infarction. Its main mechanism is to protect the microvascular structure and functional integrity. The core mechanism is to promote the activity of endothelial nitric oxide synthase and to achieve myocardial Effective reperfusion opens up new areas of research. Guided by the theory of veins, he proposed the “microvascular protection in ischemic region—a new strategy for the treatment of cerebral infarction”, which opened up new ideas and approaches for the treatment of cerebral infarction besides thrombolysis and neuroprotection. The experiment also confirmed that Tongluo intervention can effectively treat diabetic microvascular complications, showing the important guiding value of context theory for the prevention and treatment of such major diseases.

Application of context theory to explore the arrhythmia pathogenesis and treatment of traditional Chinese medicine, summed up the "Wen Qing Bu Tong" group characteristics, developed a new national drug Shensong Yang Xin capsule, for the slow treatment of arrhythmia provides an effective treatment. Application of context theory to explore the pathogenesis and treatment of chronic heart failure of traditional Chinese medicine, put forward the "gas separation", "blood", "water" mutual influence interaction is the formation of lesions aggravated the development of malignant pathological chain, the accumulation of interest and expansion of the heart, The failure of function is the result of its aggravating development. It sums up the characteristics of treating the disease by "blood water, water, water, water, and phlegm." Formulation of "Yiwenyang, Huoxuetongluo, and Lishui swelling" governing method and new drugs for Qiangqiangxin Capsule The group side, a large number of clinical and experimental studies on the above drugs support the theoretical guidance and clinical application value of the context theory in the treatment of vascular lesions.

"The Theory of Context" is another masterpiece of collateral disease research after "Combination of Diseases". The publication of monographs of Collateral Diseases established the system of collaterals, diseases, and syndromes. The Theory of Threads has systematically constructed context theory from The "collateral syndrome management" to "context theory" reflect the continuous deepening of the research on collaterals and a new stage of discipline development. "The Threads Theory" can be said to be based on traditional Chinese medicine as the main subject of multi-disciplinary cooperation and research results, both in the original theoretical basis of traditional Chinese medicine has a major original theoretical innovation, but also drawing on the forefront of scientific research on vascular lesions, but also for modern high-tech conditions The development of the basic theory of traditional Chinese medicine provides a useful reference.

Short comment

Make theoretical research more clinical

Ren Zhuang

Doctors in the Qing Dynasty had the theory of collaterals and veins. Today there is a new book on the theory of context in Chinese medicine, and the national 973 plan has made significant progress in the original study of the theories of special therapies of traditional Chinese medicine. Under the guidance of context theory, prevention and treatment of cardiovascular and cerebrovascular diseases, "Tongxinluo", "Shensong Yangxin", "Xunqiang" prescription highlights the effect of evidence-based medicine to verify. The value of innovation in context theory is that it directly serves the clinic, and its core theory, “leveling management of occupational health,” enables traditional blood theory to be passed on and developed.

The Theory of Threads presented from the core theory of context theory and related experimental and clinical research results, to the differentiation treatment of common diseases of the "choroids and vascular system diseases", to experimental and clinical research of representative prescriptions, theoretical elaboration system, and practical summary complete. These contents reflect the distinct characteristics of the innovative development of the context theory, namely the “theory-clinical-new medicine” integrated development model. It not only inherits and explores traditional Chinese medicine theory, but also closely combines clinical practice and experimental research, and actively applies modern science and technology and therapeutic efficacy evaluation methods. , to form a timely feedback between theoretical research and clinical verification, is of great significance to continuously improve the theory, guide clinical application, and innovate TCM theory.

Theoretical research and innovation are the “soul” and “basestone” of the development of traditional Chinese medicine. The theoretical innovation of traditional Chinese medicine must focus on the needs of clinical diagnosis and treatment. It can directly or indirectly help and guide clinical practice, and can be validated in the evaluation system of therapeutic efficacy. However, in the current field of theoretical study of traditional Chinese medicine, there is still a combination of theoretical research and clinical practice, modern laboratory, test and evaluation methods are not widely used, Western medicine related research results to absorb the phenomenon of insufficient integration. Therefore, the innovative mode of context theory is worthy of deep thinking and learning from the industry.

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