Mysterious bark ingredients are expected to treat common lung cancer

Release date: 2007-08-17

Mysterious bark ingredients are expected to treat common lung cancer Researchers at the University of Texas Southwestern Medical Center recently published a research article saying they have discovered some active ingredients in the bark of the South American Lapacho tree that can kill Certain types of cancer cells. At the same time, the researchers also pointed out that the compound may also be used to treat the most common type of lung cancer. The compound is named beta-lapachone (reference translation: beta-lapacoon). The compound exhibits good anti-cancer properties and researchers are testing its efficacy on human pancreatic cancer. But so far, no researchers have revealed the mechanism by which this compound kills cancer cells. Professor David Boothman is the moderator of the study, and he published the results of the study in the journal Proceedings of the National Academy of Sciences. It is worth mentioning that Professor David Boothman has studied the compound and its mechanism of killing cancer cells for 15 years. In this study, Boothman and his colleagues at the Simmons Cancer Center found that beta-lapacoin interacts with an enzyme called NQO1. NQO1 exhibits high levels of expression in non-small cell lung cancer as well as in some other solid tumors. Among tumors, β-Lampacoin is involved in the metabolism of the NQO1 enzyme and thus contributes to the death of cancer cells. In contrast, since the NQO1 enzyme is not expressed in non-cancerous tissues, this compound does not affect the function of normal tissues.
—— Information from: Medio

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